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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a5490dba6dc07d4487f35669a4333245908feb1f50d7cbbdad348f9a7bf97d' 
  AND token = 'gC1rFWL4wbTiHpIQzXUcNuYxC3dG1MhjWWhnfxc1KGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}