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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad3560ef3b08750915b4d8fb5e49af1c8f40ef9c1a618eda4a2986d00265e57' 
  AND token = 'BE7/MefWtc04Wd/QgjuxlIZECs+cMQ45Wd6mCeD4IDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}