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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8425609b45221477022a2d2681637a0f69ebc9f6b9fdd5a67a72dacd6adeb2b' 
  AND token = 'feow6HTnJcTytTojO+1QXYFxzbV3KNzEoTbOHmePq94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}