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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af3f8de92b530943291669ae681f61f9f5b2099bec71ce43ca1c839ccbccd32' 
  AND token = 'OXXbmArdh+5vN011433nLlQA51WMt7duEO25EIG+TbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}