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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3729f933741147ede774cf4ecf3db4c372e0fdcfa8ce91932a149fb49203a49' 
  AND token = '/rVy2VBt9w0BuoBrgk7Vk9F6EFwMPtX4kmNABAYwtL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}