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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01181d19b5a9bef6678fdaeacfd31b00e24bce0859c2b3d1ff07d99f61271712' 
  AND token = '6lmitpuiW8kKz1b2JSxgIfDZ5cyCxG8PgGu3tmsLmIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}