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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f170deeb0375ef64baab3f158bb6db96acf635bcb5d063cba3b5b06abdfed2c' 
  AND token = 'lUzYCmPmi3dc1hE1G3uV7a40OKEx7baXUUgQ5u0MZpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}