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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ccad7abb5bddbb9c35bc140eb01af51e12de6492a4ade0b1860a272bf79bd0' 
  AND token = 'TxSrqQEJV6eZi55mLW5xoVxcaihyBbEvatsfSniMtH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}