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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642a013cf12de48bae999305e793b0c5d0dca1a90404d0dd47a98c4c574bb468' 
  AND token = 'I5boIvF2x9P5EeOq6mLvcJWjkwZit/LyIsS/3PW37zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}