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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6448d69d8f1aec1bb08241ee4f6238e72bc73ac4e173327a75f5484bd73108' 
  AND token = 'C12q4QZlwH9S1QKhnxC4OT97UPA7ka9IXG6J0oU3/x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}