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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490ece3aa78c982373eaad601724d3d04bb6b488ddc98307a073e1cc16147c29' 
  AND token = 'LNVPsAltPEIOyTzHz3KJilrnsvQrdgoyyXhcUKP3+YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}