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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5810c9382d626f20f1b77d9acda637af67e8854e6c800e4d101ca1976d1eac50' 
  AND token = 'ko6ldPYvw6gmBUdKj3xLpS8u6PIRcq1gU+VXic+GjG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}