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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '414d88887b8aa1828a9c9ebb4e94c1b4e6a9441d72aad4a4a61f99a2a297ad02' 
  AND token = '8VXnmrcns7Y2UC4UQPICjuFoYO1F+1gQf4vd0Fz+yRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}