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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3cde6545e9284e2bbb38773bc786df2526b8ba7d48d7cb4d3937cca28bfc69d' 
  AND token = 'OiS/2VePmiPQhkAN4xNf9Bp79xxD3IibSW2PdMIgSmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}