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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26270f2653aaa17f4996853b1db2456c43da5c1f0bbdd679f7d2aecbd993f7e6' 
  AND token = 'kqntcbB6Jtj/tPSRju+lnRCxnoyISqPhDor5918+pnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}