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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3677d778a4e6ab9d57a777ddd60255f72e4f88c194c3ca9b9d060c4e9f75c86f' 
  AND token = 'xsVsEmD6TaI62glcl4hHe0prQqq9gOCeDUaRKt5X+Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}