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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db79a5e8045e6b2f2e8a3a320d2d3ed84842b54bc26e946cd338f6a2454a21d' 
  AND token = 'MLmlIeb140R+EfP2Er/u21wMObV+B859yOsRYOGvxFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}