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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '512490e7a838970ef10ff704d7db645e05fb4aa182ef2558ebd79176d8e25587' 
  AND token = 'Kxasnef/yvGmcVOGxuTWHk9kH2z+QkKKXx0ShWaUCtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}