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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a43022d1bd6ad8ee167532f751106eb424b1480da103fe2fa83398a4ee89bd5' 
  AND token = 'nhbW2A5QaDqibmxB302DMh1DAsQmjm7xdFbYrW7uq7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}