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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6c52d2e7db371d6310dfc151181318b144aac6046d6c1e5fbc241c5d1eac16' 
  AND token = 'R0OhMc+bvIhqJ3zYDorHtJrtYq5acxKUq3Z2PViE3dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}