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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e685eeec218bb62664717c0320927a1d4ed177f2abf53353106168e5d6eabe7' 
  AND token = '+trs//RqgKXfgnvqwgZ3S1Vs3p7fwpRin7e2o+SaPuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}