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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f73cba96d7cf3fbcbb582c95d06214083773844665d8eb16ed4cd408c8da8a1' 
  AND token = 'K6HCvaOVaxNkbuRDC21azyAey7KRMXoPTI+GSZ2waKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}