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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4366c3eb43c29701e7164175e245c25f74524949612429921ed1273d6b6a2bbc' 
  AND token = 'pf7q3KZ3SDaB7jnVA6lnAfSVEH6ptUE+kpIh7QT2bPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}