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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a856a443e4bb0867fbb354e56b37e4a20f417cd8d8514cfac1c30a9491684360' 
  AND token = 'uANq84R3zJirg0qiXsUb7/JUtx6pASiJNIZM5x4YCSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}