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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd57edcc6574c83b8809e8fb443881041f08a017f1c377a05bac831d53d38894' 
  AND token = 'H+z7cYkrSNpXAuG77GLoTnBkgM4a7xSAfDeQWOpGfiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}