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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586c16000a8b08131edb59d10ec7751c2a9e01936348450b5d5d75824a55a003' 
  AND token = '5NkLswhjdFFg9YSVKYZfScYPafUuKRkMYLzSJI53yhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}