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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d4b22fc305aab96ba872b830b059b53e5de3e4e99990107674ebf70a49082d' 
  AND token = 'QyyphOSDoI71vP9RG40REbvpGOwlYlitSw826E5UVck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}