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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45e1205eab806444928b8704ce8e33b71954a93bc1b1ebf7f4462d4cadab6f3' 
  AND token = 'vNzTcax1C11S0LZLoZcH4FsEsH7+IBie2fJBfbdQr3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}