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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f1d7b24ce42d619bdc5ebe96498b6e0fac72392e461fe68a2e0b66b472df0eb' 
  AND token = '1YSOm9LtqaxIoTUcvjW2MSk8NxMn1dEocVIzQfaIUlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}