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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78fd5e619b455ca07d5e80d0014ce11cb03abd671438ff83b88866c5146e6df0' 
  AND token = 'AHUSrlRr1b9DnH6QHRn7HNb+0QEb0XWy6T3HY41Dgrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}