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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4406b04a5e8a912bda82adb15ef64daa0e103c30a5baa738e4c9b75868b05ba3' 
  AND token = 'pfuOYFoP87eENKB/EZNHqjxxDTpFm/lOW+RzeWWB/4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}