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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d653c9fe2608ca8d95e2a1e595e4e13761d42713a6c2a258f44168ebdfd8eb6' 
  AND token = 'w+o51jFmvLSgwwDp3WLYS0a4U1+7UdZoImkH7uXXaFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}