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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd4452527c3effead317e2939afe3a17308949d0d09c39b6845ebee87c1a404' 
  AND token = '4vR82UKr44UIgXa466mXUaZqj14xlEL7a3rxK8fzboc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}