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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0db1dc8d30559f751cc03a539487409f0cb124e566116499d02f500645714c' 
  AND token = 'GMTev77q4u1UIONYWwLzNvc+EIZkk/FgDlS5m5UwHYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}