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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc4fb46d048e3c840b03a680214a0b9680118c9bb1e131e7bdcc76ba7496875' 
  AND token = '4VveW8fxCMPG/S3DDXpB9aX0Pcj/QMxmQDAw8U0zn6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}