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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b92ed78a282380ab615ab11f1b6c21750e0bc6e539c1ff281fbbee4a333541cd' 
  AND token = 'iGW2TfHZp+nKQIyFwsQx2V/NUBiP7KKBaMrpeD79Sys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}