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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b29e29402a1957e6b37cf49c855f2b0dc03b26d45e5d378dd4c9d09bb336e9' 
  AND token = 'YH8/vZwn9kEkF9227uBiSHAMG6hdjnRBD7FNi4hLT34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}