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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0166a27d124b62fe35a20c64e4d4e9bae11bdf15f2f27547feabdd5b3208b04c' 
  AND token = 'j2jY9my03VFvnbWHOLt49DkGvaz76D/2xLx0CrJQtEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}