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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916009ca771e844553b88a688f02090194e194e9cb2653e14be0857a4ad5b6ae' 
  AND token = '/eq+Kc9rArw8LSqKv8gqT9OfLKTlBh/Jhz1gBle1N3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}