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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d38bb2e1f2f9b6458903885533b21adedb2a2f1b13968ed8e02994fc5c7359b' 
  AND token = '1wg5qTX5S9biU1DU0OYVXl4AazoMFk7p1ntOJ7UI/fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}