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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2419821b3a4efdc35d0a82602fa5d59a7fb1f83bbd0e6fa361bfa75f1ee2b198' 
  AND token = 'lsnAcubW8mtWL07tUiUyfP2DF6sjjuYTBN16SAUmfG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}