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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aad216f18734c31ab5518127c5d230eb118a6fc269310e0391025b0479e7866' 
  AND token = 'YB2CUyP2ePWjy/Fv8HimVTDRIx5Lat9cHJ4RU8AmTQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}