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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7564246226b3cc7bb6a1b753af101cfa0db9ed29d2e42a91b5df8f12533b4c95' 
  AND token = '5xzpQV1guDX6YeMbt6XI0HFOuwtD2+OQOMIMDwZJzv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}