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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d386930b72815e9dbcd1514a1f262f249679a761e6d9bd55260a07b0e285215' 
  AND token = 'IXkbhy7oJSh94u90ji6YdDRroIuvXOx5i1Hx9y3BPPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}