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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4384e1de1dfb0182379df329ac9e14d528f1cd5cc9a8b59a02dad3f526978ded' 
  AND token = '+ya1Nxo/de8jbUVgbp7rk3fUIJIrQRxJkYFdkM8iYRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}