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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d7d0bd40b793695e8deb77f92def0adb58530ad851e8c69e18e46e4bfe699b5' 
  AND token = '81PMMW8da17E0iVQc9DBEJZveHtsEU/wN9qcs3+2u7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}