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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '242fcbc18c6f110980b0503d7eb2d6cf9f9c9afd28e02e729488f80dc9b87b55' 
  AND token = 'LqPaH8TfvBuWV0CycnSdYJXSLHDZd+7WpOHXtQteXOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}