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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f926fee64dd5ad9a09e51d7565e062e6954689f6abbfaa1d28c52c788b4276d8' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}