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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a01c0bf22b7543b97de54b4ca294029fcb834af7256cfefe5a151200257384f' 
  AND token = '/ZcWbOXUOY/4N+ve6VuWoerf5jCnU+qICCkmSWsjT0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}