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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755ee3f2d961a88e027e6350d138cd3f62f15ca7b73a809185b07a6bb75b77c0' 
  AND token = '364HZMqsMMfyT2v/8WvxWFCBEJmgH90k2Pw0j3BnhXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}